University of Southern California immunization requirements
The short answer
To enroll at University of Southern California, students generally need proof of MMR, Varicella, Tdap, MenACWY, Hep B. Records due before registration; clinical programs have an earlier onboarding deadline. Miss the deadline and registration hold until immunization compliance is met.
All students
Required for every enrolled student.
| Vaccine | What's required |
|---|---|
| MMR (measles, mumps, rubella) | 2 doses or immunity (campus policy) |
| Varicella (chickenpox) | 2 doses or immunity (campus policy) |
| Tdap (tetanus, diphtheria, pertussis) | 1 dose within 10 years (campus policy) |
| Meningococcal conjugate (MenACWY) | 1 dose on or after age 16 for incoming students under 22 |
| Hepatitis B | Series recommended; required for health-sciences students |
Recommended
Not required to register, but advised by the campus health center.
| Vaccine | What's required |
|---|---|
| COVID-19 | Per current USC campus policy |
| Influenza (seasonal) | Recommended annually; required in clinical settings |
Nursing, medical & allied-health students
Keck School of Medicine, the school of pharmacy and nursing students complete an annual clinical clearance through the health-sciences campus. This is an occupational-health clearance in everything but name — titers, TB screening and annual boosters tied to a clinical site.
| Vaccine | What's required |
|---|---|
| Hepatitis B | Completed series + titer |
| Tuberculosis screening | IGRA at onboarding + annual screening |
| Varicella (chickenpox) | Titer required for clinical clearance |
| Influenza (seasonal) | Annual influenza vaccine |
What a hold means. Registration hold until immunization compliance is met. Students who submit complete records before the deadline avoid any disruption to registration or move-in.
California state context
California has no statewide college immunization law. Instead the University of California and California State University systems set systemwide requirements — typically Hepatitis B for students under 19, plus MMR, varicella, Tdap and meningococcal — and each campus health center administers holds and compliance.
Frequently asked
What immunizations are required to enroll at University of Southern California?
University of Southern California students generally must show proof of MMR, Varicella, Tdap, MenACWY, Hep B. Records due before registration; clinical programs have an earlier onboarding deadline. If records are missing, registration hold until immunization compliance is met.
Is the meningococcal (MenACWY) vaccine required at University of Southern California?
students must either receive a MenACWY dose on or after age 16 or sign an informed declination. It is strongly expected for students living in residence halls.
What do nursing and health-professions students at University of Southern California need beyond the standard vaccines?
Keck School of Medicine, the school of pharmacy and nursing students complete an annual clinical clearance through the health-sciences campus. On top of the all-student list they typically complete Hep B, TB, Varicella, Flu — often with titers proving immunity rather than dose history.
What happens if I don't submit my immunization records to University of Southern California?
Registration hold until immunization compliance is met. Most campuses block enrollment in the following term until the record is cleared.
About this page. This is an illustrative concept page generated by Enterprise Health to demonstrate a programmatic requirements library. Vaccine lists are representative examples, not official guidance — always confirm current requirements with the University of Southern California student health center and your program before submitting records.
This is what Enterprise Health manages for campus health teams
One certified record tracks every student's immunizations, titers and clearances — and places (and clears) the registration holds automatically, across every program.