Regulators & Standards Bodies

FMCSAFederal Motor Carrier Safety Administration

The DOT agency that regulates commercial motor carriers, including driver medical fitness and drug/alcohol testing.

Reviewed June 2026 by Enterprise Health

Key facts

  • DOT agency regulating commercial motor carriers and drivers.
  • Runs the National Registry of Certified Medical Examiners for DOT physicals.
  • Sets driver drug/alcohol testing (Part 382) and the Drug & Alcohol Clearinghouse.

What it means

FMCSA administers the Federal Motor Carrier Safety Regulations in Title 49 CFR, covering CDL standards, hours of service, driver qualification (Part 391) and drug/alcohol testing (Part 382). It maintains the National Registry of Certified Medical Examiners who perform DOT physicals and the Drug & Alcohol Clearinghouse. Carriers track examiner certifications, exam expirations and random-testing pools in their occupational-health record.

Frequently asked

Who can perform a DOT physical?

Only a clinician listed on FMCSA's National Registry of Certified Medical Examiners. The exam produces a medical examiner's certificate valid for up to 24 months.

What does FMCSA regulate beyond medical exams?

FMCSA sets CDL standards, hours of service, driver qualification (Part 391) and drug/alcohol testing (Part 382), and runs the Drug & Alcohol Clearinghouse. Carriers track exam expirations and random-testing pools to stay compliant.

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